Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23193195 | 0.96 | OPRM1 (0.34) | FOLH1OPRM1MMP2MMP9MMP8 | |
| SCHEMBL22561301 | 0.81 | — | — | |
| SCHEMBL21137502 | 0.80 | MMP2 (0.30) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL27189806 | 0.78 | FOLH1 (0.34) | FOLH1OPRM1MMP2MMP9MMP8 | |
| SCHEMBL22561265 | 0.78 | — | — | |
| SCHEMBL22561476 | 0.77 | FOLH1 (0.34) | FOLH1OPRM1 | |
| SCHEMBL25045543 | 0.76 | PARP14 (0.31) | — | |
| SCHEMBL22618763 | 0.76 | FOLH1 (0.34) | FOLH1OPRM1 | |
| SCHEMBL31697409 | 0.74 | EPHX2 (0.36) | TSHRSMN1; SMN2 | |
| SCHEMBL25696350 | 0.74 | EPHX2 (0.36) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024123914-A1 | PROCESS FOR MAKING ANTIBODY-DRUG CONJUGATES | MERCK SHARP & DOHME LLC (US) | 2024-06-13 | — | — | WO | disclosed |