Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 13/20 | 0.55 |
| ▸ | MEN1 | O00255 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740986 | 0.76 | MEN1 (0.56) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2741001 | 0.76 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2741006 | 0.75 | MEN1 (0.55) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2741015 | 0.75 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2740987 | 0.75 | MEN1 (0.55) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2740952 | 0.74 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2740989 | 0.74 | MEN1 (0.52) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2740976 | 0.74 | PSMD14 (0.53) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2740948 | 0.74 | L3MBTL1 (0.55) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL2740990 | 0.74 | L3MBTL1 (0.57) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088772-B2 | Sulfonamides and their use as a medicament | THE GENETICS COMPANY, INC. (CH) | 2012-01-03 | — | — | US | disclosed |