Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11301568 | 0.85 | HTR2A (0.52) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL19554277 | 0.82 | HTR2A (0.54) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL409598 | 0.81 | HTR2A (0.59) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL5526504 | 0.80 | HTR2A (0.58) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL26374 | 0.79 | GAA (0.65) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL25067331 | 0.79 | HTR2A (0.46) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL13069276 | 0.78 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL25764 | 0.78 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL24606 | 0.78 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAASMN1; SMN2 | |
| SCHEMBL763025 | 0.78 | HTR2A (0.57) | HTR2ABCL9CTNNB1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4622947-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | Dana-Farber Cancer Institute, Inc. (US) | 2025-10-01 | — | — | EP | disclosed |
| WO-2024112754-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-30 | — | — | WO | disclosed |
| WO-2024112754-A1 | ENAMINE N-OXIDE TOOLS FOR TARGET IDENTIFICATION APPLICATIONS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-05-30 | — | — | WO | disclosed |