SCHEMBL27411319

SCHEMBL27411319

CC(C)(C)OC(=O)COc1ccc(-c2ccc(OCc3ccccc3)nc2OCc2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ PTPN1 P18031 3/20 0.47
▸ MAPT P10636 4/20 0.42
▸ KDM4E B2RXH2 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ PLA2G4B P0C869 1/20 0.41
▸ GSTP1 P09211 1/20 0.41
▸ LMNA P02545 2/20 0.40
▸ CNR1 P21554 1/20 0.39
▸ MCL1 Q07820 2/20 0.39
▸ BAK1 Q16611 1/20 0.39
▸ MAOB P27338 1/20 0.38
▸ PRMT5 O14744 1/20 0.38
▸ NPC1 O15118 1/20 0.38
▸ CASP3 P42574 1/20 0.38
▸ SENP8 Q96LD8 1/20 0.38
▸ SENP7 Q9BQF6 1/20 0.38
▸ SENP6 Q9GZR1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25033937 0.89 FFAR4 (0.40) PTPN1GSTP1CNR1MCL1BAK1
SCHEMBL30257492 0.89 PTPN1 (0.43) PTPN1MAPTLMNAMCL1BAK1
SCHEMBL25123736 0.83 KDM4E (0.42) PTPN1MAPTKDM4EMEN1KMT2A
SCHEMBL25079220 0.83 HDAC1 (0.52) PTPN1MEN1KMT2APRMT5
SCHEMBL25123208 0.83 SUCNR1 (0.42) MAPTKDM4EMEN1KMT2A
SCHEMBL25123488 0.83 SUCNR1 (0.42) MAPTKDM4EMEN1KMT2A
SCHEMBL25123002 0.82 BCHE (0.48) PTPN1MAPTKDM4EMEN1KMT2A
SCHEMBL30817313 0.82 CA12 (0.48) PTPN1MAPTKDM4EMEN1KMT2A
SCHEMBL25123718 0.81 BCHE (0.49) PTPN1MAPTKDM4EMEN1KMT2A
SCHEMBL31152762 0.81 L3MBTL1 (0.45) MEN1KMT2ACNR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207415-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2024-06-27 — — US disclosed
WO-2024102810-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR MONTELINO THERAPEUTICS, INC. (US) 2024-05-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207415-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 PTPN1 4061/4885MAPT 3246/4885KDM4E 669/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback