Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3174802 | 0.79 | RIPK1 (0.50) | ALDH1A1ALOX5TSHRHSD17B10EPHX2 | |
| SCHEMBL8515456 | 0.78 | ALDH1A1 (0.46) | ALDH1A1ALOX5TSHRHSD17B10RIPK1 | |
| SCHEMBL4461644 | 0.75 | ALDH1A1 (0.40) | ALDH1A1ALOX5TSHRHSD17B10EPHX2 | |
| SCHEMBL11401067 | 0.74 | CTSS (0.46) | ALDH1A1ALOX5TSHRLMNARIPK1 | |
| SCHEMBL30317189 | 0.74 | SLC1A3 (0.42) | ALDH1A1ALOX5TSHRHSD17B10EPHX2 | |
| SCHEMBL12812535 | 0.74 | ALDH1A1 (0.46) | ALDH1A1ALOX5TSHRRIPK1TDP1 | |
| SCHEMBL6565710 | 0.73 | ALDH1A1 (0.41) | ALDH1A1ALOX5TSHRHSD17B10EPHX2 | |
| Bicarbonate SCHEMBL29658892 | 0.73 | ALDH1A1 (0.52) | ALDH1A1ALOX5TSHRHSD17B10EPHX2 | |
| SCHEMBL28099582 | 0.72 | ALDH1A1 (0.42) | ALDH1A1ALOX5EPHX2RIPK1TDP1 | |
| SCHEMBL9461933 | 0.72 | SMN1; SMN2 (0.45) | ALDH1A1ALOX5TSHRHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091741-A | Tartronic acid and acetal ether thereof and O-ester | DOMPE FARMACEUTICI SPA (IT) | 1994-09-07 | — | — | CN | disclosed |