SCHEMBL2741276

SCHEMBL2741276

CC(C)CC(C)N(Cc1cc(C(C)(C)C)cc(C(C)(C)C)c1O)c1ccc(Nc2ccc(Nc3ccc(Nc4ccc(CC(C)CC(C)(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
HIF1A Q16665 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2812384 1.00 CYP1A2 (0.32) CYP1A2CYP2D6HIF1ACYP2C19
SCHEMBL12875832 1.00 CYP1A2 (0.32) CYP1A2CYP2D6HIF1ACYP2C19
SCHEMBL14963226 0.97 CYP1A2 (0.30) CYP1A2CYP2D6HIF1A
SCHEMBL16509947 0.91 CYP1A2 (0.30) CYP1A2CYP2D6HIF1A
SCHEMBL9912694 0.91 HSPA5 (0.36) CYP1A2CYP2D6HIF1ACYP2C19
SCHEMBL12890010 0.89
SCHEMBL14468762 0.89 CYP1A2 (0.30) CYP1A2CYP2D6HIF1A
SCHEMBL13407247 0.89 CYP1A2 (0.30) CYP1A2CYP2D6HIF1A
SCHEMBL9912716 0.88
SCHEMBL14468734 0.88 CYP1A2 (0.30) CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9388120-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2016-07-12 US disclosed
US-9388120-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2016-07-12 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS POLNOX CORPORATION (US) 2014-10-23 US disclosed
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS POLNOX CORPORATION (US) 2014-10-23 US disclosed
US-20130130955-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2013-05-23 US disclosed
US-8080689-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2011-12-20 US disclosed
US-7799948-B2 stabilizers for inhibiting oxidation in organic materials, lubricants and petroleum based products, plastics and elastomers, cosmetics, foods and cooking oils POLNOX CORPORATION (US) 2010-09-21 US disclosed
US-7799948-B2 stabilizers for inhibiting oxidation in organic materials, lubricants and petroleum based products, plastics and elastomers, cosmetics, foods and cooking oils POLNOX CORPORATION (US) 2010-09-21 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
WO-2007064843-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2007-06-07 WO disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS CAT, LPO, DUOX1 CYP1A2 668/4885CYP2D6 934/4885HIF1A 505/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.