Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15730603 | 0.68 | ALDH1A1 (0.54) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL6142168 | 0.65 | DPP4 (0.43) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL25253368 | 0.63 | RAB9A (0.44) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL22349081 | 0.63 | ALDH1A1 (0.38) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL23386882 | 0.63 | ALDH1A1 (0.38) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL3185680 | 0.63 | DDB1 (0.41) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL9981117 | 0.63 | GRM2 (0.45) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL7976342 | 0.63 | ALDH1A1 (0.34) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL23022464 | 0.63 | DDB1 (0.41) | ALDH1A1KDM4EGLAGAATSHR | |
| SCHEMBL358722 | 0.63 | DPP4 (0.44) | ALDH1A1KDM4EGLAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1104422-C | Guanidinyl heterocycle compounds useful as alpha-2 adrenoceptor agonists | PROCTER & GAMBLE (US) | 2003-04-02 | — | — | CN | disclosed |