SCHEMBL27414019 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	CTSS	P25774	7/20	0.48

▸	CTSK	P43235	6/20	0.48

▸	SYK	P43405	1/20	0.47

▸	HDAC1	Q13547	1/20	0.44

▸	CTSB	P07858	2/20	0.43

▸	PTGS2	P35354	1/20	0.43

▸	CTSL	P07711	1/20	0.43

▸	PPARA	Q07869	2/20	0.42

▸	PPARG	P37231	1/20	0.42

▸	ATM	Q13315	1/20	0.41

▸	MEN1	O00255	1/20	0.41

▸	GAA	P10253	1/20	0.41

▸	KMT2A	Q03164	1/20	0.41

▸	ACE	P12821	1/20	0.41

▸	MALT1	Q9UDY8	1/20	0.41

▸	IDO1	P14902	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL266022	0.92	CTSK (0.51)	CTSSCTSKSYKCTSBCTSL
SCHEMBL118384	0.92	CTSK (0.51)	CTSSCTSKSYKCTSBCTSL
SCHEMBL266021	0.92	CTSK (0.51)	CTSSCTSKSYKCTSBCTSL
SCHEMBL29182105	0.87	MEN1 (0.49)	CTSSCTSKHDAC1CTSBMEN1
SCHEMBL7269720	0.86	SYK (0.46)	CTSSCTSKSYKCTSBCTSL
SCHEMBL2798709	0.86	PPARG (0.44)	CTSSCTSKSYKCTSBCTSL
SCHEMBL25045524	0.85	CTSS (0.46)	CTSSCTSKSYKCTSLATM
SCHEMBL30771263	0.85	SYK (0.43)	CTSSCTSKSYKPPARAPPARG
SCHEMBL30771337	0.85	AAK1 (0.48)	CTSSCTSKSYKMEN1GAA
SCHEMBL23564593	0.85	GAA (0.46)	SYKPPARAPPARGATMMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024130689-A1	2-FLUOROBIPHENYL-4-ACETIC ACID DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF	江苏普莱医药生物技术有限公司	2024-06-27	—	—	WO	disclosed