Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.51 |
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266022 | 1.00 | CTSK (0.51) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL266021 | 1.00 | CTSK (0.51) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL27414019 | 0.92 | CTSS (0.48) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL12028293 | 0.90 | CTSK (0.50) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL20777776 | 0.89 | CTSS (0.50) | CTSKCTSSSYKATMMALT1 | |
| SCHEMBL5669913 | 0.88 | CTSK (0.49) | CTSKCTSSSYKATMMALT1 | |
| SCHEMBL7760725 | 0.88 | CTSK (0.49) | CTSKCTSSSYKMEN1GAA | |
| SCHEMBL27406072 | 0.88 | SYK (0.52) | CTSKCTSSSYKKMT2AATM | |
| SCHEMBL6531538 | 0.88 | SYK (0.52) | CTSKCTSSSYKKMT2AATM | |
| SCHEMBL7757520 | 0.88 | CTSK (0.49) | CTSKCTSSSYKMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL JIANGSU PHARMACEUTICAL CO LTD (CN) | 2025-11-13 | — | — | US | disclosed |
| EP-3845276-B1 | BETA-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND USE OF THE SAME | IND TECH RES INST (TW) | 2025-01-29 | — | — | EP | disclosed |
| CN-113121443-B | Beta-amino acid derivatives, kinase inhibitors and pharmaceutical compositions containing them and their use | 财团法人工业技术研究院 | 2024-07-09 | — | — | CN | disclosed |
| CN-117551004-A | Synthesis method of amino acid and amino alcohol compound | 四川大学 | 2024-02-13 | — | — | CN | disclosed |
| WO-2023226965-A1 | ROCK INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2023-11-30 | — | — | WO | disclosed |
| US-20230159538-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | GLOBAL BLOOD THERAPEUTICS, INC. | 2023-05-25 | — | — | US | disclosed |
| US-11608319-B2 | Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and method for performing an in vivo related application that benefits from the inhibition of a kinase | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2023-03-21 | — | — | US | disclosed |
| US-20230065368-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | FORMA THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
| EP-4126876-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | Global Blood Therapeutics, Inc. (US) | 2023-02-08 | — | — | EP | disclosed |
| US-20220363645-A1 | BETA-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND METHOD FOR PERFORMING AN IN VIVO RELATED APPLICATION THAT BENEFITS FROM THE INHIBITION OF A KINASE | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2022-11-17 | — | — | US | disclosed |
| WO-2007076423-A2 | INHIBITORS OF Akt ACTIVITY | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| CN-1148367-C | Amidine derivatives, their preparation and application as medicines and pharmaceutical compositions containing same | ��ѧ�о���Ӧ����ѯ��˾ | 2004-05-05 | — | — | CN | disclosed |
| US-20040049008-A1 | Templated molecules and methods for using such molecules | NUEVOLUTION A/S (DK) | 2004-03-11 | — | — | US | disclosed |
| US-20030143561-A1 | Nucleoside derivatives for library preparation | NUEVOLUTION A/S (DK) | 2003-07-31 | — | — | US | disclosed |
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5273982-A | An amidinoaryleneamidoalkylpiperazinyleneacetic acid | HOFFMANN-LA ROCHE INC. (US) | 1993-12-28 | — | — | US | disclosed |
| US-5102667-A | Antiallergens, antiinflammatory agents, nervous system disorders, immunology, psychological disorders | RHONE-POULENC SANTE (FR) | 1992-04-07 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |
| EP-0386839-A2 | Tetrahydroquinoline derivatives useful for neurodegenerative disorders | MERCK SHARP & DOHME LTD. (GB) | 1990-09-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346616-A1 | ROCK INHIBITORS AND USES THEREOF | ROCK1, ROCK2, RHOA | CTSK 1192/4885CTSS 2671/4885SYK 1211/4885 |
| US-20040049008-A1 | Templated molecules and methods for using such molecules | INTS6, ABL1, INMT | CTSK 2238/4885CTSS 1399/4885SYK 2280/4885 |
| US-20230065368-A1 | INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X | USP9X, USP19, USP39 | CTSK 877/4885CTSS 693/4885SYK 4090/4885 |
| US-20030143561-A1 | Nucleoside derivatives for library preparation | PNP, SAMHD1, DCTD | CTSK 2345/4885CTSS 2836/4885SYK 4491/4885 |
| US-11608319-B2 | Beta-amino acid derivative, kinase inhibitor and pharmaceutical composition containing the same, and method for performing an in vivo related application that benefits from the inhibition of a kinase | CSNK1A1, CSNK1D, CSNK1G3 | CTSK 694/4885CTSS 1647/4885SYK 749/4885 |
| US-20220363645-A1 | BETA-AMINO ACID DERIVATIVE, KINASE INHIBITOR AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME, AND METHOD FOR PERFORMING AN IN VIVO RELATED APPLICATION THAT BENEFITS FROM THE INHIBITION OF A KINASE | CSNK1A1, CSNK1D, CSNK1G3 | CTSK 694/4885CTSS 1647/4885SYK 749/4885 |
| US-20230159538-A1 | PYRROLIDINE-PYRAZOLES AS PYRUVATE KINASE ACTIVATORS | PDK1, PDK2, PKM | CTSK 2102/4885CTSS 4325/4885SYK 1331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.