Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 4/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27414114 | 0.84 | CA12 (0.45) | HSD17B10MAPTALOX15CASP1CASP7 | |
| SCHEMBL27565927 | 0.84 | TSHR (0.41) | HSD17B10MAPTTSHRIAPPALDH1A1 | |
| SCHEMBL27501902 | 0.82 | CYP4F2 (0.56) | HSD17B10IAPPALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL27446763 | 0.80 | TSHR (0.46) | HSD17B10LMNATSHRIAPPCA12 | |
| SCHEMBL27831060 | 0.79 | MTNR1A (0.44) | IAPPALOX5PTGS2MTNR1AMMP2 | |
| Hydrochloric Acid SCHEMBL27541293 | 0.77 | MTNR1A (0.43) | IAPPALOX5PTGS2MTNR1AMMP2 | |
| SCHEMBL6670265 | 0.77 | MEN1 (0.47) | MAPTIAPPMMP2 | |
| SCHEMBL18591613 | 0.76 | LMNA (0.56) | HSD17B10MAPTLMNATSHRALDH1A1 | |
| SCHEMBL11216869 | 0.75 | IAPP (0.46) | HSD17B10MAPTLMNATSHRIAPP | |
| SCHEMBL6782219 | 0.73 | CYP2D6 (0.56) | MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1253442-C | Novel thiazine and pyrazine derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-04-26 | — | — | CN | disclosed |
| CN-1098838-C | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 2003-01-15 | — | — | CN | disclosed |
| CN-1372553-A | Novel thiazine or pyrazine derivatives | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-10-02 | — | — | CN | disclosed |
| CN-1140709-A | Substituted N- (indole-2-carbonyl) -beta-alaninamides and derivatives as antidiabetics | PFIZER (US) | 1997-01-22 | — | — | CN | disclosed |