SCHEMBL6670265

SCHEMBL6670265

Nc1cccc(CCCC(=O)O)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HDAC3 O15379 1/20 0.47
MAPK1 P28482 1/20 0.47
ADRA1A P35348 1/20 0.47
HDAC4 P56524 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HDAC1 Q13547 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HDAC7 Q8WUI4 1/20 0.47
HDAC2 Q92769 1/20 0.47
HDAC10 Q969S8 1/20 0.47
HDAC11 Q96DB2 1/20 0.47
HDAC8 Q9BY41 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HDAC9 Q9UKV0 1/20 0.47
HDAC5 Q9UQL6 1/20 0.47
MMP2 P08253 1/20 0.46
HMGB1 P09429 1/20 0.44
TBXAS1 P24557 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6248978 0.89 MMP2 (0.48) MMP2HMGB1IAPPPTGER1PTGER4
SCHEMBL27831060 0.88 MTNR1A (0.44) MEN1KMT2AMMP2HMGB1IAPP
Hydrochloric Acid SCHEMBL27541293 0.86 MTNR1A (0.43) MEN1KMT2AMMP2HMGB1IAPP
SCHEMBL197022 0.84 HDAC3 (0.57) MEN1KMT2AHDAC3MAPK1ADRA1A
SCHEMBL16795917 0.82 IAPP (0.61) MEN1KMT2AHDAC3MAPK1ADRA1A
Hydrochloric Acid SCHEMBL7434059 0.82 HDAC3 (0.55) MEN1KMT2AHDAC3MAPK1ADRA1A
SCHEMBL23077768 0.81 MEN1 (0.46) MEN1KMT2AHDAC3MAPK1ADRA1A
SCHEMBL1667991 0.81 MEN1 (0.46) MEN1KMT2AHDAC3MAPK1ADRA1A
SCHEMBL23077766 0.81 MEN1 (0.46) MEN1KMT2AHDAC3MAPK1ADRA1A
SCHEMBL11503498 0.81 MEN1 (0.46) MEN1KMT2AHDAC3MAPK1ADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107141232-A A kind of preparation method of ubenimex 国药集团川抗制药有限公司 2017-09-08 CN claimed
CN-1159185-A Method for producing beta-amino alcohol HOFFMANN LA ROCHE (CH) 1997-09-10 CN claimed
JP-9328428-A None JP disclosed
JP-8301896-A None JP disclosed
CN-110072883-A The relevant peptide of therapeutic MOTS-C 科巴公司 2019-07-30 CN disclosed
CN-109689010-A Blue powder and its purposes in cosmetics 莱雅公司 2019-04-26 CN disclosed
CN-105283439-B The dibenzoylhydrazine of boracic 英特瑞克斯顿股份有限公司 2018-02-02 CN disclosed
CN-107406373-A Boron-containing diacylhydrazine compounds 英特瑞克斯顿股份有限公司 2017-11-28 CN disclosed
CN-107141232-A A kind of preparation method of ubenimex 国药集团川抗制药有限公司 2017-09-08 CN disclosed
CN-104447394-B Novel synthesis process of ubenimex 成都傲飞生物化学品有限责任公司 2017-01-18 CN disclosed
CN-105283439-A BORON-CONTAINING DIACYLHYDRAZINES INTREXON CORP 2016-01-27 CN disclosed
CN-1039321-C New beta-amino-alpha-hydroxycarboxylic acids and their use SANKYO CO (JP) 1998-07-29 CN disclosed
CN-1188106-A Process for preparation of 3-amino-2-hydroxy-4-phenylbutyronitrile derivatives KURARAY CO (JP) 1998-07-22 CN disclosed
JP-H09328428-A MEDICINE COMPRISING TRIPEPTIDE DERIVATIVE CONTAINING AHPBA AS ACTIVE INGREDIENT SANKYO CO LTD 1997-12-22 JP disclosed
CN-1159185-A Method for producing beta-amino alcohol HOFFMANN LA ROCHE (CH) 1997-09-10 CN disclosed
JP-H08301896-A HIV PROTEASE-INHIBITING AGENT SHIONOGI & CO LTD 1996-11-19 JP disclosed
CN-1091432-A Can suppress the active peptide of hiv protease, its preparation with and medical use SANKYO CO (JP) 1994-08-31 CN disclosed
CN-1064683-A New beta-amino-alpha-hydroxycarboxylic acids and uses thereof SANKYO CO (JP) 1992-09-23 CN disclosed
CN-1016341-B NOVEL SPERGUALIN-RELATED COMPOUNDS AND PROCESS FOR PRODUCING THE SAME MICROBIAL CHEMICAL RESEARCHING (JP) 1992-04-22 CN disclosed
CN-87102538-A New compound relevant and preparation method thereof with spergualin 1987-11-18 CN disclosed