Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23108875 | 0.80 | LMNA (0.32) | MAP4K1LMNA | |
| SCHEMBL23108633 | 0.80 | LMNA (0.32) | MAP4K1LMNA | |
| SCHEMBL23107347 | 0.74 | MAP4K1 (0.32) | MAP4K1LMNA | |
| SCHEMBL23106882 | 0.74 | MAP4K1 (0.32) | MAP4K1LMNA | |
| SCHEMBL23106904 | 0.74 | MAP4K1 (0.32) | MAP4K1LMNA | |
| SCHEMBL27414736 | 0.73 | MAPK1 (0.44) | L3MBTL1LMNA | |
| SCHEMBL23089487 | 0.72 | ALDH1A1 (0.34) | MAP4K1LMNA | |
| SCHEMBL23133738 | 0.70 | CPB2 (0.38) | MAP4K1L3MBTL1LMNA | |
| SCHEMBL23103528 | 0.70 | CPB2 (0.38) | MAP4K1L3MBTL1LMNA | |
| SCHEMBL23114542 | 0.70 | MAP4K1 (0.32) | MAP4K1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125812-A1 | SUBSTITUTED PYRIMIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND MEDICAL USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-06 | — | — | WO | disclosed |