SCHEMBL2741477

SCHEMBL2741477

c1ccc2c(-n3c4ccccc4c4ccc5c(c6ccccc6n5-c5cc(-n6c7ccccc7c7ccccc76)nc(-n6c7ccccc7c7ccccc76)c5)c43)ccnc2c1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PIK3R2 O00459 9/20 0.35
ADRB2 P07550 1/20 0.34
NCF1 P14598 1/20 0.34
PTPN1 P18031 2/20 0.32
AR P10275 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
KCNH2 Q12809 2/20 0.32
MKNK1 Q9BUB5 1/20 0.31
MKNK2 Q9HBH9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2741463 0.86 KDM4E (0.36) PIK3R2ADRB2NCF1KDM4EATM
SCHEMBL2741479 0.85 KDM4E (0.41) KDM4EATML3MBTL1
SCHEMBL2741460 0.83 KDM4E (0.36) PIK3R2ADRB2NCF1KDM4EL3MBTL1
SCHEMBL2741464 0.82 KDM4E (0.49) KDM4EATML3MBTL1
SCHEMBL2741480 0.81 KDM4E (0.37) KDM4EATML3MBTL1
SCHEMBL2741462 0.77 GRM4 (0.39) KDM4EATML3MBTL1KCNH2
SCHEMBL13087007 0.76 ATM (0.42) KDM4EATML3MBTL1MKNK1MKNK2
SCHEMBL17245308 0.75 KDM4E (0.49) ADRB2NCF1PTPN1ARKDM4E
SCHEMBL17248206 0.74 KDM4E (0.41) KDM4EATML3MBTL1MKNK1MKNK2
SCHEMBL17248209 0.74 KDM4E (0.41) KDM4EATML3MBTL1MKNK1MKNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3176241-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT Nippon Steel & Sumikin Chemical Co., Ltd. (JP) 2017-06-07 EP disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2015-06-18 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8993129-B2 Fluorescence and delayed fluorescence-type organic light-emitting material and element NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-03-31 US disclosed
US-8962158-B2 Material having indolocarbazole compound for phosphorescent light-emitting element and organic electroluminescent element using the same NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-02-24 US disclosed
US-8962158-B2 Material having indolocarbazole compound for phosphorescent light-emitting element and organic electroluminescent element using the same NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) 2015-02-24 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120241732-A1 ORGANIC LIGHT-EMITTING MATERIAL AND ORGANIC LIGHT-EMITTING ELEMENT NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-09-27 US disclosed
US-20120001165-A1 MATERIAL FOR PHOSPHORESCENT LIGHT-EMITTING ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-05 US disclosed
US-20120001165-A1 MATERIAL FOR PHOSPHORESCENT LIGHT-EMITTING ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150166886-A1 FLUORESCENCE AND DELAYED FLUORESCENCE-TYPE ORGANIC LIGHT-EMITTING MATERIAL AND ELEMENT LEF1, EML4, TEAD1 PIK3R2 4738/4885ADRB2 4039/4885NCF1 385/4885
US-20120001165-A1 MATERIAL FOR PHOSPHORESCENT LIGHT-EMITTING ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME LEF1, ELOC, ELP1 PIK3R2 3809/4885ADRB2 1970/4885NCF1 1312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.