Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | ANPEP | P15144 | 2/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | SAT1 | P21673 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11765569 | 0.95 | PKM (0.50) | PKMKDM4ECYP2C19KMT2AMEN1 | |
| SCHEMBL11765853 | 0.92 | PKM (0.48) | PKMKDM4ECYP2C19KMT2ACYP1A2 | |
| SCHEMBL12977299 | 0.91 | PKM (0.39) | PKMKDM4ECYP2C19KMT2AMEN1 | |
| SCHEMBL2242929 | 0.90 | TSHR (0.46) | PKMKDM4EKMT2AALDH1A1ANPEP | |
| SCHEMBL27415012 | 0.89 | KDM4E (0.42) | PKMKDM4EKMT2AALDH1A1ANPEP | |
| SCHEMBL4293846 | 0.88 | PKM (0.40) | PKMKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL17351928 | 0.88 | TSHR (0.52) | PKMKDM4EALDH1A1ANPEPERAP2 | |
| SCHEMBL24459668 | 0.86 | ANPEP (0.50) | PKMALDH1A1ANPEPERAP2TSHR | |
| SCHEMBL6249621 | 0.86 | ANPEP (0.50) | PKMALDH1A1ANPEPERAP2TSHR | |
| SCHEMBL7325532 | 0.86 | ANPEP (0.50) | PKMALDH1A1ANPEPERAP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024119037-A1 | NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES COMPRISING THE SAME | UNIVERSITY OF CINCINNATI (US) | 2024-06-06 | — | — | WO | disclosed |