SCHEMBL2242929

SCHEMBL2242929

CCCCNCC(O)CC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 3/20 0.42
PKM P14618 1/20 0.41
ANPEP P15144 2/20 0.40
ERAP2 Q6P179 1/20 0.40
CYP3A4 P08684 1/20 0.38
KDM4E B2RXH2 2/20 0.37
ADH1B P00325 1/20 0.36
ADH1C P00326 1/20 0.36
ADH1A P07327 1/20 0.36
ADH7 P40394 1/20 0.36
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
S1PR2 O95136 5/20 0.32
S1PR4 O95977 5/20 0.32
S1PR1 P21453 5/20 0.32
S1PR3 Q99500 5/20 0.32
S1PR5 Q9H228 1/20 0.32
EPHX1 P07099 2/20 0.32
ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17351928 0.93 TSHR (0.52) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL27705619 0.91 ANPEP (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL27705519 0.91 ANPEP (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL7325532 0.91 ANPEP (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL27726084 0.91 ANPEP (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL24459668 0.91 ANPEP (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL6249621 0.91 ANPEP (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL27705506 0.91 ANPEP (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL20592385 0.90 TSHR (0.50) TSHRALDH1A1PKMANPEPERAP2
SCHEMBL11765569 0.90 PKM (0.50) TSHRALDH1A1PKMANPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105481744-A CO2/N2-H2O2 dual-stimulation response surfactant and preparation method thereof UNIV JIANGNAN 2016-04-13 CN claimed
US-20150367277-A1 Alkanolamine-Based Carbon Dioxide Absorbent Containing Polyalkylene Glycol Monomethyl Ether, and Carbon Dioxide Absorption Method and Separation Method Using Same UNIVERSITY-INDUSTRY COOPERATION FOUNDATION OF KYUNG HEE UNIVERSITY (KR) 2015-12-24 US claimed
CN-111971269-B Reaction of glycolaldehyde 塔明克私人有限公司 2024-02-13 CN disclosed
US-11851390-B2 Reaction of glycoladehyde TAMINCO BVBA 2023-12-26 US disclosed
US-20210139410-A1 REACTION OF GLYCOLADEHYDE TAMINCO BVBA (BE) 2021-05-13 US disclosed
EP-3774717-A1 REACTION OF GLYCOLALDEHYDE TAMINCO BVBA (BE) 2021-02-17 EP disclosed
CN-111971269-A Reaction of glycolaldehyde 塔明克公司 2020-11-20 CN disclosed
EP-3290401-B1 N-SUBSTITUTED ACYCLIC ETHYLENE DIAMINES TAMINCO BVBA (BE) 2020-09-23 EP disclosed
WO-2019193117-A1 REACTION OF GLYCOLALDEHYDE KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2019-10-10 WO disclosed
EP-3290401-A1 N-SUBSTITUTED ACYCLIC ETHYLENE DIAMINES Taminco bvba (BE) 2018-03-07 EP disclosed
CN-105481744-A CO2/N2-H2O2 dual-stimulation response surfactant and preparation method thereof UNIV JIANGNAN 2016-04-13 CN disclosed
EP-2000489-B1 CURABLE AQUEOUS COMPOSITION KANSAI PAINT CO LTD (JP) 2010-07-28 EP disclosed
EP-2000489-A9 CURABLE AQUEOUS COMPOSITION Kansai Paint Co., Ltd. (JP) 2009-03-11 EP disclosed
EP-2000489-A2 CURABLE AQUEOUS COMPOSITION Kansai Paint Co., Ltd. (JP) 2008-12-10 EP disclosed
US-20080053835-A1 Monomer Compound, Process for Producing the Same, Polymer Thereof, and Water-Based Curable Composition KANSAI PAINT CO., LTD. (JP) 2008-03-06 US disclosed
EP-1798218-A1 MONOMER COMPOUND, PROCESS FOR PRODUCING THE SAME, POLYMER THEREOF, AND WATER-BASED CURABLE COMPOSITION KANSAI PAINT CO., LTD. (JP) 2007-06-20 EP disclosed
WO-2003019383-A1 CRYSTALLINE ALUMINOPHOSPHATE PRODUCTION PROCESS AND CRYSTALLINE ALUMINOPHOSPHATE SHOWA DENKO KK (JP) 2003-03-06 WO disclosed
EP-0519747-B1 Cement admixture and defoaming agent GRACE W R & CO (US) 1996-09-04 EP disclosed
EP-0519747-A2 Cement admixture and defoaming agent W.R. Grace & Co.-Conn. (US) 1992-12-23 EP disclosed
US-5156679-A Water soluble alkylated alkanolamine salts W. R. GRACE & CO.-CONN. (US) 1992-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851390-B2 Reaction of glycoladehyde ADH1A, ADH1C, GRHPR TSHR 3008/4885ALDH1A1 26/4885PKM 1907/4885
US-20080053835-A1 Monomer Compound, Process for Producing the Same, Polymer Thereof, and Water-Based Curable Composition THEM6, PAM, WEE1 TSHR 4460/4885ALDH1A1 741/4885PKM 1730/4885
US-20210139410-A1 REACTION OF GLYCOLADEHYDE ADH1A, ADH1C, GRHPR TSHR 3008/4885ALDH1A1 26/4885PKM 1907/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.