SCHEMBL7325532

SCHEMBL7325532

CCCCCCNCC(O)CC

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.50
ERAP2 Q6P179 1/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
PKM P14618 1/20 0.43
S1PR2 O95136 5/20 0.42
S1PR4 O95977 5/20 0.42
S1PR1 P21453 5/20 0.42
S1PR3 Q99500 5/20 0.42
S1PR5 Q9H228 1/20 0.42
EPHX1 P07099 8/20 0.41
ADH1B P00325 1/20 0.41
ADH1C P00326 1/20 0.41
ADH1A P07327 1/20 0.41
ADH4 P08319 1/20 0.41
ADH7 P40394 1/20 0.41
GNAI3 P08754 1/20 0.38
GNAO1 P09471 1/20 0.38
GNAI1 P63096 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27705519 1.00 ANPEP (0.50) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL27705619 1.00 ANPEP (0.50) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL27726084 1.00 ANPEP (0.50) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL6249621 1.00 ANPEP (0.50) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL27705506 1.00 ANPEP (0.50) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL24459668 1.00 ANPEP (0.50) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL17351928 0.98 TSHR (0.52) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL11765853 0.93 PKM (0.48) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL2242929 0.91 TSHR (0.46) ANPEPERAP2ALDH1A1TSHRPKM
SCHEMBL8381104 0.91 TSHR (0.55) ANPEPERAP2ALDH1A1TSHRPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150367277-A1 Alkanolamine-Based Carbon Dioxide Absorbent Containing Polyalkylene Glycol Monomethyl Ether, and Carbon Dioxide Absorption Method and Separation Method Using Same UNIVERSITY-INDUSTRY COOPERATION FOUNDATION OF KYUNG HEE UNIVERSITY (KR) 2015-12-24 US claimed
US-10611826-B2 Affinity chromatography matrix LABORATOIRE FRANÇAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES (FR) 2020-04-07 US disclosed
US-20180142036-A1 COMPOSITION ENRICHED IN ANTI-A AND/OR ANTI-B POLYCLONAL IMMUNOGLOBULINS FOR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES OR POLYCYTHEMIA LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES (FR) 2018-05-24 US disclosed
US-20180100023-A1 Composition Enriched in Anti-A and /or Anti B Polyclonal Immunoglobulins LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOTECHNOLOGIES (FR) 2018-04-12 US disclosed
US-20150367277-A1 Alkanolamine-Based Carbon Dioxide Absorbent Containing Polyalkylene Glycol Monomethyl Ether, and Carbon Dioxide Absorption Method and Separation Method Using Same UNIVERSITY-INDUSTRY COOPERATION FOUNDATION OF KYUNG HEE UNIVERSITY (KR) 2015-12-24 US disclosed
US-8802448-B2 Mixed mode ligands PALL CORPORATION (US) 2014-08-12 US disclosed
CN-101184830-B Lubricating oil composition IDEMITSU KOSAN CO 2013-03-13 CN disclosed
US-20130030154-A1 MIXED MODE LIGANDS PALL CORPORATION (US) 2013-01-31 US disclosed
EP-2551013-A1 Mixed mode ligands Pall Corporation (US) 2013-01-30 EP disclosed
CN-101184830-A Lubricating oil composition IDEMITSU KOSAN CO (JP) 2008-05-21 CN disclosed
EP-0287696-B1 ISOQUINOLINE DERIVATIVES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1991-01-02 EP disclosed
US-4798897-A (AMINOALKYL)AMINOSULFONYL-SUBSTITUTED CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1989-01-17 US disclosed
EP-0287696-A1 Isoquinoline derivatives Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1988-10-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180142036-A1 COMPOSITION ENRICHED IN ANTI-A AND/OR ANTI-B POLYCLONAL IMMUNOGLOBULINS FOR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES OR POLYCYTHEMIA SSB, FCGR3B, FCGR2A ANPEP 1518/4885ERAP2 2697/4885ALDH1A1 3833/4885
US-10611826-B2 Affinity chromatography matrix FCGR3B, FCGR2A, HLA-DRB1 ANPEP 448/4885ERAP2 973/4885ALDH1A1 3761/4885
US-20130030154-A1 MIXED MODE LIGANDS NCL, NECTIN4, NCLN ANPEP 1725/4885ERAP2 4669/4885ALDH1A1 3975/4885
US-20180100023-A1 Composition Enriched in Anti-A and /or Anti B Polyclonal Immunoglobulins FCGR3B, APOB, FCGR2A ANPEP 466/4885ERAP2 1289/4885ALDH1A1 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.