Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 17/20 | 0.76 |
| ▸ | MMP13 | P45452 | 17/20 | 0.76 |
| ▸ | MMP2 | P08253 | 2/20 | 0.65 |
| ▸ | MMP3 | P08254 | 2/20 | 0.65 |
| ▸ | MMP9 | P14780 | 2/20 | 0.65 |
| ▸ | MMP8 | P22894 | 2/20 | 0.65 |
| ▸ | MMP12 | P39900 | 1/20 | 0.65 |
| ▸ | MMP14 | P50281 | 1/20 | 0.65 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6869740 | 0.95 | MMP1 (0.77) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL16013385 | 0.91 | MMP1 (0.62) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL2575324 | 0.91 | MMP1 (0.79) | MMP1MMP13MMP2MMP3MMP9 | |
| Hydroxyamine SCHEMBL5914587 | 0.89 | MMP1 (0.76) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL27448685 | 0.88 | MMP1 (0.64) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7886290 | 0.87 | MMP1 (0.62) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6056972 | 0.87 | MMP1 (0.60) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL6962773 | 0.86 | MMP1 (1.00) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL12076481 | 0.86 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 | |
| SCHEMBL7208011 | 0.86 | MMP1 (0.80) | MMP1MMP13MMP2MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1113862-C | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2003-07-09 | — | — | CN | claimed |
| CN-1249743-A | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2000-04-05 | — | — | CN | claimed |
| CN-1113862-C | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2003-07-09 | — | — | CN | disclosed |
| CN-1249743-A | Arylsulfonylamino hydroxamic acid derivs | PFIZER PROD INC (US) | 2000-04-05 | — | — | CN | disclosed |