Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685859 | 0.80 | KEAP1 (0.56) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL5694881 | 0.78 | TDP1 (0.54) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL4192865 | 0.77 | FFAR1 (0.60) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL156142 | 0.76 | KEAP1 (0.64) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL8665089 | 0.76 | KEAP1 (0.64) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| SCHEMBL4141193 | 0.76 | KEAP1 (0.64) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| Phenylethyl Alcohol SCHEMBL7240959 | 0.76 | TDP1 (0.94) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| Phenyl Propionic Acid SCHEMBL9122761 | 0.75 | KEAP1 (0.95) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| Phenyl Propionic Acid SCHEMBL8901632 | 0.75 | KEAP1 (0.95) | TDP1KEAP1ALDH1A1FFAR1HDAC2 | |
| Phenyl Propionic Acid SCHEMBL5314808 | 0.75 | KEAP1 (0.95) | TDP1KEAP1ALDH1A1FFAR1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1117291-A | 4-Hydroxy-pyran-2-one derivatives for the treatment of retroviral infections | UPJOHN CO (US) | 1996-02-21 | — | — | CN | disclosed |