Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4141193 | 0.82 | KEAP1 (0.64) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| Hydrogen Peroxide SCHEMBL10839871 | 0.81 | TDP1 (0.71) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| Hydrogen Peroxide SCHEMBL10839772 | 0.81 | TDP1 (0.71) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| SCHEMBL28617812 | 0.79 | GRIN1 (0.48) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| SCHEMBL1603029 | 0.78 | KEAP1 (0.58) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| Phenyl Propionic Acid SCHEMBL13618844 | 0.78 | KEAP1 (1.00) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| SCHEMBL10530175 | 0.78 | ALDH1A1 (0.67) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| SCHEMBL7269710 | 0.78 | KEAP1 (0.58) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| SCHEMBL13082819 | 0.78 | KEAP1 (0.58) | KEAP1ALDH1A1FFAR1TDP1HDAC2 | |
| Phenyl Propionic Acid SCHEMBL3419 | 0.78 | KEAP1 (1.00) | KEAP1ALDH1A1FFAR1TDP1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686685-B1 | Photochromic dye | RODENSTOCK OPTIK G (DE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0686685-A2 | Photochromic dye | Optische Werke G. Rodenstock (DE) | 1995-12-13 | — | — | EP | disclosed |