SCHEMBL156142

SCHEMBL156142

O=C(CO)CCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.64
ALDH1A1 P00352 2/20 0.59
FFAR1 O14842 2/20 0.59
TDP1 Q9NUW8 3/20 0.56
TRPA1 O75762 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
HDAC2 Q92769 2/20 0.55
HDAC8 Q9BY41 2/20 0.55
HDAC6 Q9UBN7 2/20 0.55
HDAC1 Q13547 2/20 0.54
HDAC3 O15379 1/20 0.54
MAPK1 P28482 1/20 0.54
ADRA1A P35348 1/20 0.54
HDAC4 P56524 1/20 0.54
SLC6A3 Q01959 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27831457 0.89 HDAC1 (0.69) KEAP1ALDH1A1FFAR1TDP1L3MBTL1
SCHEMBL497371 0.88 KEAP1 (0.73) KEAP1ALDH1A1FFAR1TDP1TRPA1
SCHEMBL15929719 0.87 MAPT (0.68) KEAP1TDP1HDAC2HDAC8HDAC6
SCHEMBL107423 0.86 KEAP1 (0.70) KEAP1ALDH1A1FFAR1TDP1TRPA1
SCHEMBL712597 0.86 KEAP1 (0.70) KEAP1ALDH1A1FFAR1TDP1TRPA1
SCHEMBL5247648 0.85 MAPT (0.71) TDP1TRPA1HDAC2HDAC8HDAC6
SCHEMBL13536907 0.85 KEAP1 (0.57) KEAP1ALDH1A1FFAR1TDP1TRPA1
SCHEMBL26624571 0.84 KEAP1 (0.61) KEAP1ALDH1A1FFAR1TDP1TRPA1
SCHEMBL19561359 0.84 HDAC1 (0.69) KEAP1ALDH1A1FFAR1TDP1TRPA1
SCHEMBL28062036 0.84 KEAP1 (0.61) KEAP1ALDH1A1FFAR1TDP1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 436 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 EP claimed
CN-114381441-B Enzymatic synthesis of chiral amino alcohol compounds 中国科学院天津工业生物技术研究所 2023-09-08 CN claimed
WO-2023144326-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 WO claimed
WO-2022105986-A1 NOVEL COOLING AGENTS AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO claimed
WO-2022106452-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2022-05-27 WO claimed
CN-114381441-A Enzymatic synthesis of chiral amino alcohol compounds 中国科学院天津工业生物技术研究所 2022-04-22 CN claimed
CN-112852771-B Enzymatic synthesis of chiral amino alcohol compounds 中国科学院天津工业生物技术研究所 2022-04-08 CN claimed
EP-3413906-B1 CANCER TREATMENT COMBINATION COMPOSITIONS, METHODS AND USES UNIV LOUISIANA STATE (US) 2021-10-27 EP claimed
EP-3853203-A1 HYDROLYTICALLY LABILE PRO-FRAGRANCES CONTAINING alfa, beta UNSATURATED ESTERS Henkel AG & Co. KGaA (DE) 2021-07-28 EP claimed
EP-2075320-A1 Method for manufacturing an aroma concentrate and aroma concentrate Symrise GmbH & Co. KG (DE) 2009-07-01 EP claimed
US-20090155446-A1 PROCESS FOR THE PREPARATION OF A FLAVORING CONCENTRATE, AND A FLAVORING CONCENTRATE SYMRISE GMBH & CO. KG (DE) 2009-06-18 US claimed
US-20080262452-A1 STANDALONE SMART DISPOSABLE DIAPER, KIT AND METHOD NEUROPHYSIOLOGICAL CONCEPTS LLC 2008-10-23 US claimed
US-20080262453-A1 REMOTE MONITORING DIAPER SYSTEM, KIT AND METHOD OF USING NEUROPHYSIOLOGICAL CONCEPTS LLC 2008-10-23 US claimed
WO-2007083071-A2 PROCESS FOR PREPARING A PRECURSOR OF AN AROMATIC COMPOUND BY BIOSYNTHESIS INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE - INRA (FR) 2007-07-26 WO claimed
WO-2006087370-A1 USE OF AROMA GLYCOSIDES AS FLAVOR OR FRAGRANCE INGREDIENT POALIS A/S (DK) 2006-08-24 WO claimed
CN-1254527-C Fabric care compositions systems for delivering clean, fresh scent in lipophilic fluid treatment process PROCTER & GAMBLE (US) 2006-05-03 CN claimed
US-6849591-B1 Microcapsule preparations and detergents and cleaning agents containing microcapsules BASF AKTIENGESELLSCHAFT (DE) 2005-02-01 US claimed
CN-1433461-A Fabric care compositions and systems for delivering clean and fresh scent during lipophilic fluid treatment PROCTER & GAMBLE (US) 2003-07-30 CN claimed
CN-1111149-C Use of mixtures of 1-o-hydroxyphenylbutanone and 1-p-hydroxyphenylbutanone LAIYANG AGRICULTURAL COLLEGE (CN) 2003-06-11 CN claimed