Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7346867 | 0.81 | SLC6A2 (0.46) | KCNH2KDM4EALDH1A1PMP22NPSR1 | |
| SCHEMBL7322803 | 0.74 | KCNH2 (0.45) | KCNH2DRD4RAB9A | |
| SCHEMBL7346874 | 0.73 | KCNH2 (0.46) | KCNH2ALDH1A1HTR4 | |
| SCHEMBL7453934 | 0.73 | CA12 (0.49) | KDM4E | |
| SCHEMBL11497213 | 0.72 | GPR84 (0.51) | KCNH2 | |
| SCHEMBL7346871 | 0.71 | KCNH2 (0.46) | KCNH2DRD4RAB9A | |
| SCHEMBL8919065 | 0.71 | CA12 (0.56) | KDM4EALDH1A1 | |
| SCHEMBL7383392 | 0.70 | KCNH2 (0.51) | KCNH2DRD4KDM4E | |
| SCHEMBL8921004 | 0.70 | CA12 (0.51) | KDM4E | |
| SCHEMBL7348373 | 0.70 | KCNH2 (0.45) | KCNH2KDM4EALDH1A1PMP22NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092772-A | Medicine | SMITHKLINE BEECHAM PLC (GB) | 1994-09-28 | — | — | CN | disclosed |