SCHEMBL27416397

SCHEMBL27416397

Cc1ncc(C)c(OCCl)n1

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 3/20 0.41
LMNA P02545 1/20 0.35
PDK2 Q15119 1/20 0.30
PDK4 Q16654 1/20 0.30
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9918974 0.76 LMNA (0.38) NUDT1LMNAAGXT
SCHEMBL89379 0.75 LMNA (0.40) NUDT1LMNA
SCHEMBL12795986 0.72 NUDT1 (0.34) NUDT1LMNA
SCHEMBL13211415 0.70 NUDT1 (0.34) NUDT1
SCHEMBL29451022 0.68 LMNA (0.44) LMNA
SCHEMBL22119920 0.68 LMNA (0.44) LMNA
SCHEMBL12858177 0.67 NUDT1 (0.36) NUDT1LMNAPDK2PDK4
SCHEMBL3712628 0.66
SCHEMBL25786503 0.65 MAPT (0.34) NUDT1LMNA
SCHEMBL12858035 0.65 ALDH1A1 (0.38) NUDT1LMNAPDK2AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1118464-C Noval pyrimidine derivatives and process and preparing thereof YUHAN CORP (KR) 2003-08-20 CN disclosed
CN-1251586-A Noval pyrimidine derivatives and process and preparing thereof YUHAN CORP (KR) 2000-04-26 CN disclosed