Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9241857 | 0.86 | NOTUM (0.40) | NOTUMKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL27342035 | 0.79 | NOTUM (0.47) | NOTUMKMT2AMEN1HSD17B3 | |
| SCHEMBL8689935 | 0.74 | NOTUM (0.41) | NOTUMALDH1A1HTTNPC1RAB9A | |
| SCHEMBL28381288 | 0.72 | SLC6A4 (0.42) | NOTUMKMT2AMAPT | |
| SCHEMBL27416702 | 0.71 | MAPK1 (0.44) | NOTUMKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL9868101 | 0.71 | ALDH1A1 (0.44) | NOTUMKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL21172772 | 0.69 | ALDH1A1 (0.42) | NOTUMKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL21172761 | 0.69 | ALDH1A1 (0.42) | NOTUMKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL32673424 | 0.69 | NOTUM (0.62) | NOTUMKMT2AALDH1A1HTTNPC1 | |
| SCHEMBL26818892 | 0.69 | NOTUM (0.48) | NOTUMKMT2AALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118347-A | Benzotoudened 5-ringneterocycl, preparation and phamaceutical and diagnostic use of same | HOECHST AG (DE) | 1996-03-13 | — | — | CN | disclosed |