Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31404143 | 0.71 | NOTUM (0.48) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL27178980 | 0.71 | NOTUM (0.48) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL26818531 | 0.71 | NOTUM (0.48) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL8689935 | 0.71 | NOTUM (0.41) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL31404147 | 0.71 | NOTUM (0.48) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL27416701 | 0.71 | NOTUM (0.44) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| Guanidine SCHEMBL8690427 | 0.71 | NOTUM (0.39) | MAPK1ALDH1A1NPC1HTTRAB9A | |
| SCHEMBL9868101 | 0.71 | ALDH1A1 (0.44) | ALDH1A1NPC1HTTRAB9ANOTUM | |
| SCHEMBL10065836 | 0.70 | OPRM1 (0.44) | MAPK1ALDH1A1NOTUM | |
| SCHEMBL9241857 | 0.69 | NOTUM (0.40) | MAPK1ALDH1A1NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118347-A | Benzotoudened 5-ringneterocycl, preparation and phamaceutical and diagnostic use of same | HOECHST AG (DE) | 1996-03-13 | — | — | CN | disclosed |