Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8689935 | 0.85 | NOTUM (0.41) | ALDH1A1TSHRKDM4ENOTUMNPC1 | |
| SCHEMBL4145687 | 0.84 | MEN1 (0.41) | ALDH1A1MAPTGABRG2GABRB3GABRA5 | |
| SCHEMBL23343522 | 0.81 | NR1D1 (0.50) | NR1D1NOTUM | |
| SCHEMBL4959583 | 0.81 | NR1D1 (0.50) | NR1D1NOTUM | |
| SCHEMBL28009398 | 0.80 | MAPT (0.47) | ALDH1A1TDP1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL9866691 | 0.79 | LTA4H (0.47) | MEN1KMT2AGABRA1GABRB1GABRA3 | |
| SCHEMBL9867636 | 0.79 | ALDH1A1 (0.51) | ALDH1A1MAPTTSHRSMN1; SMN2NR1D1 | |
| Hydrochloric Acid SCHEMBL8690429 | 0.78 | NOTUM (0.36) | ALDH1A1KMT2ATSHRKDM4ENOTUM | |
| SCHEMBL4150077 | 0.77 | ROCK1 (0.38) | ALDH1A1MAPTMEN1KMT2ANR1D1 | |
| SCHEMBL13077629 | 0.76 | TSHR (0.46) | ALDH1A1MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017584-A | Antidepressant 2-(4,5-dihydro-1H-imidazolyl)-dihydro-1H-indoles, -1,2,3,4-tetrahydroquinolines and -1H-indoles, and methods of use thereas | STERLING DRUG INC. (US) | 1991-05-21 | — | — | US | disclosed |