SCHEMBL27417293

SCHEMBL27417293

CC1C=Nc2c(nc(N)[nH]c2=O)C1C

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PNP P00491 2/20 0.45
QTRT1 Q9BXR0 1/20 0.37
CYP1A2 P05177 1/20 0.36
DYRK1A Q13627 1/20 0.36
TYMS P04818 8/20 0.34
XDH P47989 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL97605 0.83 PNP (0.47) PNPQTRT1CYP1A2DYRK1ATYMS
SCHEMBL21249712 0.76 PNP (0.44) PNPQTRT1CYP1A2DYRK1ATYMS
SCHEMBL21249696 0.76 PNP (0.47) PNPQTRT1CYP1A2TYMSXDH
SCHEMBL23394738 0.76 PNP (0.44) PNPQTRT1CYP1A2XDH
SCHEMBL9544019 0.69 PNP (0.36) PNPQTRT1CYP1A2DYRK1ATYMS
SCHEMBL30603282 0.63 PNP (0.36) PNPQTRT1CYP1A2DYRK1ATYMS
Hydrochloric Acid SCHEMBL9544122 0.63 PNP (0.34) PNP
SCHEMBL20968806 0.62 PNP (0.38) PNPXDH
SCHEMBL22601502 0.62 TYMS (0.37) PNPTYMS
SCHEMBL535022 0.60 QTRT1 (0.42) PNPQTRT1DYRK1ATYMSXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024092256-A2 PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-05-02 WO disclosed