Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9544122 | 0.81 | PNP (0.34) | PNP | |
| SCHEMBL9545264 | 0.73 | XDH (0.35) | PNPKDM4EALDH1A1LMNAGLA | |
| SCHEMBL20968806 | 0.71 | PNP (0.38) | PNPXDH | |
| SCHEMBL97605 | 0.71 | PNP (0.47) | PNPTYMSCYP1A2XDHQTRT1 | |
| SCHEMBL9543219 | 0.71 | PNP (0.33) | PNPKDM4ELMNAHSD17B10TYMS | |
| SCHEMBL27417293 | 0.69 | PNP (0.45) | PNPTYMSCYP1A2XDHQTRT1 | |
| Hydrochloric Acid SCHEMBL9544734 | 0.65 | DHFR (0.35) | PNPTYMS | |
| SCHEMBL9543196 | 0.65 | KDM4E (0.35) | PNPKDM4EALDH1A1LMNAHSD17B10 | |
| SCHEMBL9543827 | 0.65 | DHFR (0.34) | PNPTYMS | |
| SCHEMBL23394738 | 0.65 | PNP (0.44) | PNPKDM4EALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993020075-A1 | 8-SUBSTITUTED-N5-DEAZAPTERINS AS ANTIFOLATES | THE UNIVERSITY OF SYDNEY (AU) | 1993-10-14 | — | — | WO | disclosed |