Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 3/20 | 0.47 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 4/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27417293 | 0.83 | PNP (0.45) | PNPQTRT1XDHCYP1A2TYMS | |
| SCHEMBL23394738 | 0.79 | PNP (0.44) | PNPQTRT1XDHCYP1A2 | |
| SCHEMBL21249696 | 0.79 | PNP (0.47) | PNPQTRT1XDHCYP1A2TYMS | |
| SCHEMBL21249712 | 0.79 | PNP (0.44) | PNPQTRT1XDHCYP1A2TYMS | |
| SCHEMBL30603282 | 0.72 | PNP (0.36) | PNPQTRT1XDHCYP1A2TYMS | |
| SCHEMBL9544019 | 0.71 | PNP (0.36) | PNPQTRT1XDHCYP1A2TYMS | |
| Hydrochloric Acid SCHEMBL9544122 | 0.65 | PNP (0.34) | PNP | |
| SCHEMBL22601502 | 0.64 | TYMS (0.37) | PNPTYMS | |
| SCHEMBL20968806 | 0.64 | PNP (0.38) | PNPXDH | |
| SCHEMBL29799948 | 0.62 | CDK1 (0.37) | PNPQTRT1XDHTYMSDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3350191-B9 | NUCLEOTIDE ANALOGS | UNIV CALIFORNIA (US) | 2021-12-22 | — | — | EP | disclosed |
| EP-3875462-A1 | NUCLEOTIDE ANALOGS | The Regents of The University of California (US) | 2021-09-08 | — | — | EP | disclosed |
| EP-3350191-B1 | NUCLEOTIDE ANALOGS | UNIV CALIFORNIA (US) | 2021-05-12 | — | — | EP | disclosed |
| EP-3626866-B1 | NEXT-GENERATION SEQUENCING LIBRARIES | ABBOTT MOLECULAR INC (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20170333459-A1 | METHODS OF TREATING ORTHOPOX VIRUS INFECTIONS AND ASSOCIATED DISEASES | CHIMERIX, INC. | 2017-11-23 | — | — | US | disclosed |
| WO-2017048956-A1 | NUCLEOTIDE ANALOGS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-03-23 | — | — | WO | disclosed |
| US-20150141375-A1 | Methods of Treating Viral Associated Diseases | CHIMERIX, INC. | 2015-05-21 | — | — | US | disclosed |
| US-20130072458-A1 | Methods of Treating Viral Associated Diseases | CHIMERIX, INC. (US) | 2013-03-21 | — | — | US | disclosed |
| US-20120164104-A1 | Composition and Methods of Treating Viral Infections and Viral Induced Tumors | CHIMERIX, INC. (US) | 2012-06-28 | — | — | US | disclosed |
| US-20120058975-A1 | Phosphonate Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-03-08 | — | — | US | disclosed |
| US-20110263536-A1 | Methods of Treating Orthopox Virus Infections and Associated Diseases | CHIMERIX, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-20100173870-A1 | Phosphonate Compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072458-A1 | Methods of Treating Viral Associated Diseases | HAVCR2, EIF2AK2, TSLP | PNP 727/4885QTRT1 3931/4885XDH 591/4885 |
| US-20110263536-A1 | Methods of Treating Orthopox Virus Infections and Associated Diseases | OAT, PNPO, OTC | PNP 253/4885QTRT1 4621/4885XDH 58/4885 |
| US-20120058975-A1 | Phosphonate Compounds | PHPT1, PHOSPHO1, PIK3CA | PNP 74/4885QTRT1 3004/4885XDH 2687/4885 |
| US-20170333459-A1 | METHODS OF TREATING ORTHOPOX VIRUS INFECTIONS AND ASSOCIATED DISEASES | OAT, PNPO, OTC | PNP 253/4885QTRT1 4621/4885XDH 58/4885 |
| US-20150141375-A1 | Methods of Treating Viral Associated Diseases | HAVCR2, EIF2AK2, TSLP | PNP 727/4885QTRT1 3931/4885XDH 591/4885 |
| US-20120164104-A1 | Composition and Methods of Treating Viral Infections and Viral Induced Tumors | HAVCR2, IRF3, CCL5 | PNP 1806/4885QTRT1 4577/4885XDH 2359/4885 |
| US-20100173870-A1 | Phosphonate Compounds | PHPT1, PHOSPHO1, PIK3CA | PNP 74/4885QTRT1 3004/4885XDH 2687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.