Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | FBP1 | P09467 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448533 | 0.93 | MCL1 (0.47) | TP53HTTMEN1KMT2AAKR1C3 | |
| SCHEMBL27449998 | 0.85 | MEN1 (0.46) | TP53HTTMEN1KMT2AAKR1C3 | |
| SCHEMBL29898330 | 0.81 | TP53 (0.75) | TP53HTTMEN1KMT2AAKR1C3 | |
| SCHEMBL39098 | 0.81 | TP53 (0.75) | TP53HTTMEN1KMT2AAKR1C3 | |
| SCHEMBL4972259 | 0.81 | TP53 (0.68) | TP53HTTMEN1KMT2AAKR1C3 | |
| SCHEMBL4972255 | 0.81 | TP53 (0.68) | TP53HTTMEN1KMT2AAKR1C3 | |
| SCHEMBL7273129 | 0.78 | MEN1 (0.54) | TP53HTTMEN1KMT2AAKR1C3 | |
| SCHEMBL8307775 | 0.78 | ALOX5 (0.40) | TP53KMT2A | |
| SCHEMBL8307777 | 0.78 | ALOX5 (0.40) | TP53KMT2A | |
| SCHEMBL7277760 | 0.77 | TP53 (0.63) | TP53HTTMEN1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1097417-A | New heterogeneous ring compound | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-01-18 | — | — | CN | disclosed |