Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466188 | 0.78 | PARP1 (0.56) | ALDH1A1KMT2AGAAKDM4EPOLB | |
| SCHEMBL27450148 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2AGAAKDM4EPOLB | |
| SCHEMBL7572680 | 0.75 | PARP1 (0.46) | ALDH1A1KMT2AGAAKDM4EPOLB | |
| SCHEMBL7568945 | 0.75 | PARP1 (0.43) | ALDH1A1KMT2AGAAKDM4EPOLB | |
| SCHEMBL27417062 | 0.74 | PARP1 (0.62) | ALDH1A1GAAKDM4ECYP3A4PARP1 | |
| SCHEMBL15532332 | 0.73 | KMT2A (0.51) | ALDH1A1KMT2AGAAKDM4EPOLB | |
| SCHEMBL28555834 | 0.73 | CYP1A2 (0.60) | ALDH1A1KMT2AGAAKDM4EPOLB | |
| SCHEMBL27887074 | 0.72 | PSMD14 (0.51) | ALDH1A1KMT2AKDM4EPOLBMAPT | |
| SCHEMBL27417841 | 0.72 | TDP1 (0.43) | ALDH1A1KMT2AKDM4EPOLBTDP1 | |
| SCHEMBL27450576 | 0.71 | KMT2A (0.42) | ALDH1A1KMT2AGAAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |