Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 7/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572680 | 0.78 | PARP1 (0.46) | TDP1HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL27450149 | 0.75 | ALDH1A1 (0.60) | TDP1TERTHPGDKDM4EMEN1 | |
| SCHEMBL27417062 | 0.74 | PARP1 (0.62) | KDM4EALDH1A1PARP1 | |
| SCHEMBL24597666 | 0.74 | MEN1 (0.49) | TDP1PTGS2HPGDKDM4EMEN1 | |
| SCHEMBL13739658 | 0.73 | PTGDR2 (0.54) | TDP1HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL27887076 | 0.72 | PSMD14 (0.51) | TDP1HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL7568945 | 0.72 | PARP1 (0.43) | TSHRKDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL27417840 | 0.72 | ALDH1A1 (0.41) | TDP1HPGDKDM4EMEN1ALDH1A1 | |
| SCHEMBL14564415 | 0.70 | TDP1 (0.64) | TDP1PTGS2MEN1KMT2AAKR1B1 | |
| SCHEMBL27450577 | 0.69 | MEN1 (0.43) | TDP1TERTPTGS2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |