Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 10/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAP2 | P11137 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24198762 | 0.86 | HRH4 (0.44) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL11229272 | 0.85 | MAPT (0.47) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL523253 | 0.85 | RHEB (0.54) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL25812917 | 0.84 | HRH4 (0.48) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL29414225 | 0.83 | KMT2A (0.46) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL3064168 | 0.83 | KMT2A (0.46) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL7705452 | 0.83 | NR4A2 (0.48) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL24754421 | 0.83 | ALOX15 (0.52) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL23835759 | 0.83 | HRH4 (0.44) | HRH4HRH3KMT2AMAPTALDH1A1 | |
| SCHEMBL26241758 | 0.81 | PIN1 (0.57) | HRH4KMT2AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356387-B1 | ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS | UNIV MONASH (AU) | 2024-06-26 | — | — | EP | disclosed |