Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11216293 | 0.88 | POLB (0.48) | FABP3FABP4GAAFABP5GABRA1 | |
| SCHEMBL27538330 | 0.85 | GAA (0.42) | FABP3FABP4GAAFABP5KDM4E | |
| SCHEMBL13592557 | 0.84 | GAA (0.52) | GAALMNAKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL20915178 | 0.82 | GAA (0.50) | GAAGABRA1GABRB2LMNAKMT2A | |
| SCHEMBL14410288 | 0.78 | POLB (0.52) | FABP3FABP4GAAKDM4ELMNA | |
| SCHEMBL22012206 | 0.78 | GAA (0.46) | GAAKDM4ELMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6100378 | 0.78 | SMN1; SMN2 (0.46) | FABP3FABP4FABP5GABRA1GABRB2 | |
| SCHEMBL30013972 | 0.78 | GABRA1 (0.45) | FABP3FABP4GAAFABP5GABRA1 | |
| SCHEMBL1726368 | 0.78 | KMT2A (0.62) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7646866 | 0.77 | SMN1; SMN2 (0.47) | GAAKDM4ELMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1118457-C | Cyclic diamine compounds and medicine contg. same | KOWA CO (JP) | 2003-08-20 | — | — | CN | disclosed |
| CN-1258283-A | Cyclic diamine compounds and medicine contg. same | KOWA CO (JP) | 2000-06-28 | — | — | CN | disclosed |