Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14410288 | 0.90 | POLB (0.52) | POLBP2RX4GAAFABP3FABP4 | |
| SCHEMBL27419002 | 0.88 | FABP3 (0.52) | POLBP2RX4GAAFABP3FABP4 | |
| SCHEMBL27538330 | 0.78 | GAA (0.42) | GAAFABP3FABP4FABP5KDM4E | |
| SCHEMBL3978690 | 0.75 | KMT2A (0.50) | GAALPAR1RIPK1SMN1; SMN2NLRP3 | |
| SCHEMBL13592557 | 0.73 | GAA (0.52) | GAALPAR1SMN1; SMN2NLRP3ALDH1A1 | |
| SCHEMBL6682827 | 0.72 | GABRA1 (0.63) | GAAFABP3FABP4FABP5GABRA1 | |
| SCHEMBL20915178 | 0.72 | GAA (0.50) | GAAGABRA1GABRB2SMN1; SMN2ALDH1A1 | |
| SCHEMBL3983979 | 0.71 | CA1 (0.55) | POLBP2RX4GAANPC1CASP3 | |
| SCHEMBL6100378 | 0.71 | SMN1; SMN2 (0.46) | POLBP2RX4FABP3FABP4FABP5 | |
| SCHEMBL6354671 | 0.70 | ALDH1A1 (0.44) | KCNJ11RAB9ACA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034292-B1 | PROCESS FOR THE PREPARATION OF ANTHRANILIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-11-23 | — | — | EP | disclosed |
| EP-0034292-A2 | Process for the preparation of anthranilic acid derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-08-26 | — | — | EP | disclosed |