Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29543283 | 0.78 | PTGES2 (0.46) | TRPV4PKMPKLRNFE2L2PTGES2 | |
| SCHEMBL1515862 | 0.78 | PTGES2 (0.46) | TRPV4PKMPKLRNFE2L2PTGES2 | |
| SCHEMBL16412 | 0.78 | ALDH1A1 (0.44) | NFE2L2ALDH1A1HSD17B10TDP1AKR1B1 | |
| SCHEMBL30605911 | 0.78 | ALDH1A1 (0.44) | NFE2L2ALDH1A1HSD17B10TDP1AKR1B1 | |
| SCHEMBL14812406 | 0.77 | CCR4 (0.40) | TRPV4PKMPKLRNFE2L2PTGES2 | |
| SCHEMBL2163747 | 0.75 | EDNRB (0.36) | TRPV4PKMPKLRNFE2L2PTGES2 | |
| SCHEMBL1199464 | 0.75 | SLC40A1 (0.43) | TRPV4PKMPKLRNFE2L2PTGES2 | |
| SCHEMBL13692689 | 0.75 | PTGES2 (0.37) | TRPV4PKMPKLRNFE2L2PTGES2 | |
| SCHEMBL27152694 | 0.72 | SLC22A12 (0.39) | TRPV4PKMPKLRNFE2L2PTGES2 | |
| SCHEMBL30681743 | 0.72 | SLC22A12 (0.39) | TRPV4PKMPKLRNFE2L2PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393920-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |