Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13012200 | 0.81 | CA2 (0.50) | PTGES2CA1CA2CA9CA12 | |
| SCHEMBL2061390 | 0.79 | ADRA2A (0.38) | PTGES2GAACA1CA2CA9 | |
| SCHEMBL3425152 | 0.79 | TTR (0.50) | PTGES2GAACA1CA2CA9 | |
| SCHEMBL29543283 | 0.78 | PTGES2 (0.46) | PTGES2TRPV4PKMPKLRNFE2L2 | |
| SCHEMBL1515862 | 0.78 | PTGES2 (0.46) | PTGES2TRPV4PKMPKLRNFE2L2 | |
| SCHEMBL30605911 | 0.78 | ALDH1A1 (0.44) | NFE2L2ALDH1A1HSD17B10TDP1AKR1B1 | |
| SCHEMBL16412 | 0.78 | ALDH1A1 (0.44) | NFE2L2ALDH1A1HSD17B10TDP1AKR1B1 | |
| SCHEMBL14812406 | 0.77 | CCR4 (0.40) | PTGES2TRPV4PKMPKLRNFE2L2 | |
| SCHEMBL27419864 | 0.75 | TRPV4 (0.35) | PTGES2TRPV4PKMPKLRNFE2L2 | |
| SCHEMBL2163747 | 0.75 | EDNRB (0.36) | PTGES2TRPV4CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109539-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-11 | — | — | WO | disclosed |