Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9208788 | 0.89 | PTGS2 (0.57) | PTGS2PTGS1PGRAOC3 | |
| SCHEMBL9201549 | 0.85 | PTGS2 (0.78) | PTGS2PTGS1NR3C2AOC3 | |
| SCHEMBL9203156 | 0.85 | PTGS2 (0.78) | PTGS2PTGS1NR3C2AOC3 | |
| SCHEMBL15347055 | 0.83 | PTGS2 (0.78) | PTGS2PTGS1AOC3 | |
| Hydrochloric Acid SCHEMBL9208571 | 0.83 | PTGS2 (0.62) | PTGS2PTGS1NR3C2AOC3 | |
| SCHEMBL15346763 | 0.82 | PTGS2 (0.76) | PTGS2PTGS1AOC3 | |
| SCHEMBL9202698 | 0.82 | PTGS2 (0.60) | PTGS2PTGS1NR3C2PGRAOC3 | |
| SCHEMBL5698670 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL215235 | 0.80 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL19664982 | 0.80 | PTGS2 (0.98) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046506-C | Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-11-17 | — | — | CN | disclosed |