Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27691801 | 0.75 | CA1 (0.34) | LIPCLIPG | |
| SCHEMBL6043613 | 0.71 | LIPC (0.35) | LIPCLIPG | |
| SCHEMBL27940973 | 0.69 | PIK3CA (0.32) | — | |
| SCHEMBL12935487 | 0.68 | — | — | |
| SCHEMBL20207726 | 0.67 | TP53 (0.41) | LIPCLIPG | |
| SCHEMBL6603236 | 0.67 | GNAI3 (0.43) | LIPCLIPG | |
| SCHEMBL6603242 | 0.67 | GNAI3 (0.43) | LIPCLIPG | |
| SCHEMBL16315500 | 0.66 | S1PR1 (0.34) | LIPCLIPGS1PR1SGPL1 | |
| SCHEMBL10278211 | 0.66 | S1PR1 (0.36) | S1PR1SGPL1 | |
| SCHEMBL10513149 | 0.66 | LIPC (0.39) | LIPCLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1108301-C | Inhibitors of microsomal triglyceride transfer protein and mothed | BRISTOL MYERS SQUIBB CO (US) | 2003-05-14 | — | — | CN | disclosed |
| CN-1176640-A | Inhibitors of microsomal triglyceride transfer protein and mothed | BRISTOL MYERS SQUIBB CO (US) | 1998-03-18 | — | — | CN | disclosed |