Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7245462 | 0.84 | MAPT (0.60) | POLBMAPTALOX15TP53 | |
| SCHEMBL6950055 | 0.83 | POLB (0.49) | POLBMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL6945801 | 0.80 | MAPT (0.50) | POLBMAPTALOX15TP53 | |
| SCHEMBL9246654 | 0.72 | MAPT (0.62) | POLBMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL6945772 | 0.72 | ALOX15 (0.68) | MAPTALOX15TP53ALDH1A1CACNA1B | |
| SCHEMBL7241732 | 0.71 | MAPT (0.68) | POLBMAPTALOX15TP53 | |
| SCHEMBL10736001 | 0.71 | MAPT (0.44) | POLBMAPTALOX15TP53ALDH1A1 | |
| SCHEMBL8912934 | 0.71 | CYP2C9 (0.49) | MAPTALOX15TP53ALDH1A1KDM4E | |
| SCHEMBL9210940 | 0.67 | ALOX15 (0.43) | ALOX15ALDH1A1 | |
| SCHEMBL10661130 | 0.67 | MAPT (0.40) | POLBMAPTALOX15TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1109875-A | Phenyl-substituted 1,4-dihydropyridines | BAYER AG (DE) | 1995-10-11 | — | — | CN | disclosed |