Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | THPO | P40225 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6947853 | 0.92 | ALOX15 (0.59) | ALOX15CACNA1BCYP2C9CYP1A2CYP3A4 | |
| SCHEMBL6944706 | 0.89 | ALOX15 (0.64) | ALOX15TP53CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL6950055 | 0.86 | POLB (0.49) | ALOX15TP53CACNA1BCYP2C9CYP1A2 | |
| SCHEMBL6949599 | 0.86 | ALOX15 (0.61) | ALOX15TP53CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL6952565 | 0.83 | ALOX15 (0.61) | ALOX15TP53CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL6945817 | 0.82 | ALOX15 (0.51) | ALOX15TP53CACNA1BCYP2C9CYP1A2 | |
| SCHEMBL7275334 | 0.82 | CYP2C9 (0.70) | ALOX15TP53CACNA1BCYP2C9CYP1A2 | |
| SCHEMBL7267278 | 0.82 | CYP2C9 (0.57) | ALOX15TP53CACNA1BCYP2C9CYP1A2 | |
| SCHEMBL6950016 | 0.82 | ALOX15 (0.50) | ALOX15CACNA1BKDM4EMAPTALDH1A1 | |
| SCHEMBL9246654 | 0.81 | MAPT (0.62) | ALOX15TP53CYP2C9CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657432-B1 | Phenyl-substituted 1,4-dihydropyridines with cerebral activity | BAYER AG (DE) | 2003-03-12 | — | — | EP | claimed |