Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 12/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27427441 | 0.99 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DITGB1 | |
| SCHEMBL7733967 | 0.82 | FFAR4 (0.50) | PDE4APDE4BPDE4CPDE4DITGB1 | |
| SCHEMBL7735708 | 0.81 | THRA (0.52) | PDE4APDE4BPDE4CPDE4DADRB1 | |
| SCHEMBL27536403 | 0.81 | PTPN1 (0.54) | PDE4APDE4BPDE4CPDE4DITGB1 | |
| SCHEMBL7725094 | 0.81 | FFAR4 (0.49) | — | |
| SCHEMBL7735879 | 0.80 | PTPN1 (0.53) | PDE4APDE4BPDE4CPDE4DITGB1 | |
| SCHEMBL7735139 | 0.80 | FFAR4 (0.48) | — | |
| SCHEMBL27406192 | 0.79 | PTGER1 (0.45) | ADRB3PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL7735343 | 0.79 | PTPN1 (0.47) | PDE4APDE4BPDE4CPDE4DITGB1 | |
| SCHEMBL3892376 | 0.79 | PDE4A (0.43) | PDE4APDE4BPDE4CPDE4DITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1103332-C | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2003-03-19 | — | — | CN | disclosed |
| CN-1276778-A | Biphenyl-5-alkanoic acid derivs. and use thereof | ASAHI CHEMICAL IND (JP) | 2000-12-13 | — | — | CN | disclosed |