Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3303126 | 0.94 | GSK3B (0.49) | GSK3BSIGMAR1CA1CA2HTR1A | |
| SCHEMBL17064427 | 0.81 | SIGMAR1 (0.56) | GSK3BSIGMAR1CA1CA2HTR1A | |
| SCHEMBL3392114 | 0.79 | KMT2A (0.51) | GSK3BPOLBHSD11B1ALDH1A1MAPT | |
| SCHEMBL7287642 | 0.79 | KMT2A (0.53) | GSK3BDRD2RAB9ANPC1HSD11B1 | |
| SCHEMBL7210582 | 0.79 | NPC1 (0.56) | HTR1ADRD2HTR7DRD3RAB9A | |
| SCHEMBL7284408 | 0.79 | NPC1 (0.54) | GSK3BPOLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL7287661 | 0.78 | MAPT (0.52) | SIGMAR1POLBRAB9ANPC1ALDH1A1 | |
| SCHEMBL4580153 | 0.77 | S1PR3 (0.40) | NPC1 | |
| SCHEMBL21726649 | 0.77 | GSK3B (0.50) | GSK3BSIGMAR1CA1CA2HTR1A | |
| SCHEMBL8281524 | 0.76 | KMO (0.33) | GSK3BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217953-A1 | BICYCLIC SUBSTITUTED AROMATIC CARBOXYLIC ACID COMPOUNDS | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217953-A1 | BICYCLIC SUBSTITUTED AROMATIC CARBOXYLIC ACID COMPOUNDS | C9, CFB, C5 | GSK3B 4621/4885SIGMAR1 3856/4885CA1 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.