Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.31 |
| ▸ | ABAT | P80404 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13446666 | 0.72 | KDM4E (0.42) | ERN1HCAR2KDM4EPTGS2RAB9A | |
| SCHEMBL8461698 | 0.71 | CCR1 (0.32) | — | |
| SCHEMBL27594914 | 0.68 | CCR1 (0.30) | — | |
| SCHEMBL7472288 | 0.67 | HTR2B (0.35) | HTR2B | |
| SCHEMBL11186411 | 0.67 | LMNA (0.42) | ERN1KDM4E | |
| Hydrochloric Acid SCHEMBL28682590 | 0.65 | — | — | |
| SCHEMBL127131 | 0.65 | — | — | |
| SCHEMBL14771417 | 0.65 | BACE1 (0.31) | — | |
| SCHEMBL4018885 | 0.65 | CES2 (0.36) | KDM4EHTR2B | |
| SCHEMBL16983094 | 0.64 | ERN1 (0.41) | ERN1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130158052-A1 | PYRIMIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | MOORE II BOB M (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158052-A1 | PYRIMIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | MOORE II BOB M (US) | 2013-06-20 | — | — | US | disclosed |
| US-8324228-B2 | Pyrimidine classical cannabinoid compounds and related methods of use | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-12-04 | — | — | US | disclosed |
| US-8324228-B2 | Pyrimidine classical cannabinoid compounds and related methods of use | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2012-12-04 | — | — | US | disclosed |
| US-20120004250-A1 | PYRIMIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | MOORE II BOB M (US) | 2012-01-05 | — | — | US | disclosed |
| US-20120004250-A1 | PYRIMIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | MOORE II BOB M (US) | 2012-01-05 | — | — | US | disclosed |
| US-8022078-B2 | Pyrimidine classical cannabinoid compounds and related methods of use | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2011-09-20 | — | — | US | disclosed |
| US-8022078-B2 | Pyrimidine classical cannabinoid compounds and related methods of use | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2011-09-20 | — | — | US | disclosed |
| US-20110046163-A1 | FURANOPYRIMIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| US-20110046163-A1 | FURANOPYRIMIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2011-02-24 | — | — | US | disclosed |
| WO-2011022694-A2 | FURANOPYRIMIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2011-02-24 | — | — | WO | disclosed |
| WO-2009143182-A1 | PYRIMIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION, THE (US) | 2009-11-26 | — | — | WO | disclosed |
| US-20090286815-A1 | Pyrimidine Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
| US-20090286815-A1 | Pyrimidine Classical Cannabinoid Compounds and Related Methods of Use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158052-A1 | PYRIMIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, P2RX2 | ERN1 2118/4885HCAR2 93/4885KDM4E 1601/4885 |
| US-20090286815-A1 | Pyrimidine Classical Cannabinoid Compounds and Related Methods of Use | CNR1, CNR2, GPR18 | ERN1 2376/4885HCAR2 124/4885KDM4E 1422/4885 |
| US-20110046163-A1 | FURANOPYRIMIDINE CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, GPR17 | ERN1 3583/4885HCAR2 98/4885KDM4E 2947/4885 |
| US-20120004250-A1 | PYRIMIDINE CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, P2RX2 | ERN1 2118/4885HCAR2 93/4885KDM4E 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.