Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALPL | P05186 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621584 | 0.91 | CYP1A2 (0.57) | SMN1; SMN2KDM4EKMT2ACYP1A2ALPL | |
| SCHEMBL10680309 | 0.80 | NPC1 (0.59) | SMN1; SMN2KDM4EKMT2ACYP1A2ALPL | |
| SCHEMBL10538131 | 0.79 | PDGFRB (0.50) | SMN1; SMN2KDM4EKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL7857119 | 0.76 | CYP1A2 (0.55) | SMN1; SMN2KDM4EKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL30542307 | 0.75 | PDGFRB (0.60) | SMN1; SMN2PDGFRBPDGFRARAB9AIGF1R | |
| SCHEMBL8564487 | 0.75 | CYP1A2 (0.50) | SMN1; SMN2KDM4EKMT2ACYP1A2ALPL | |
| SCHEMBL7028923 | 0.74 | ALDH1A1 (0.70) | SMN1; SMN2KDM4EKMT2ACYP1A2ALDH1A1 | |
| Acetaldehyde SCHEMBL27299364 | 0.74 | CYP1A2 (0.79) | SMN1; SMN2KDM4EKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL5218690 | 0.74 | PDGFRB (0.49) | SMN1; SMN2KDM4EKMT2ACYP1A2ALDH1A1 | |
| SCHEMBL13302131 | 0.74 | RAB9A (0.55) | SMN1; SMN2KDM4EKMT2ACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1107144-A | Substituted heterocyclic carboxamide esters, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |
| CN-1107145-A | Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals | HOECHST AG (DE) | 1995-08-23 | — | — | CN | disclosed |