Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 11/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 11/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 11/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
| ▸ | CYBB | P04839 | 1/20 | 0.38 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.38 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.38 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.38 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27430717 | 1.00 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CHPGDROCK2 | |
| SCHEMBL27430718 | 1.00 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CHPGDROCK2 | |
| SCHEMBL27248311 | 0.85 | HPGD (0.58) | HPGDL3MBTL1MAPTCYBBNOX5 | |
| SCHEMBL27429987 | 0.82 | MAPT (0.48) | HPGDROCK2L3MBTL1MAPTNPC1 | |
| SCHEMBL27248325 | 0.81 | HPGD (0.54) | HPGDL3MBTL1MAPTCYBBNOX5 | |
| SCHEMBL27429930 | 0.80 | L3MBTL1 (0.60) | HPGDROCK2L3MBTL1MAPTCYBB | |
| SCHEMBL27429469 | 0.80 | HPGD (0.45) | HPGDROCK2L3MBTL1MAPTNPC1 | |
| SCHEMBL27248392 | 0.78 | HPGD (0.50) | HPGDMAPTALDH1A1 | |
| SCHEMBL17716933 | 0.76 | HTR2C (0.50) | HPGDL3MBTL1MAPTCYBBNOX4 | |
| SCHEMBL23867520 | 0.75 | TDP1 (0.48) | HPGDROCK2MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |