Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 4/20 | 0.41 |
| ▸ | HTR6 | P50406 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27248311 | 0.76 | HPGD (0.58) | HRH4HTR2AL3MBTL1HPGDMAPT | |
| SCHEMBL27429699 | 0.74 | EGFR (0.51) | — | |
| SCHEMBL27429475 | 0.73 | HRH4 (0.47) | HRH4HTR6 | |
| SCHEMBL27248325 | 0.73 | HPGD (0.54) | HRH4HTR2AL3MBTL1HPGDMAPT | |
| SCHEMBL27248392 | 0.71 | HPGD (0.50) | HRH4HTR2AHPGDKDM4EMAPT | |
| SCHEMBL27429480 | 0.70 | PDE4A (0.47) | HRH4HTR6 | |
| SCHEMBL27430034 | 0.68 | HTR2C (0.48) | HRH4HTR2AL3MBTL1HPGDMEN1 | |
| SCHEMBL27248330 | 0.67 | L3MBTL1 (0.58) | HRH4HTR2AL3MBTL1HPGDMAPT | |
| SCHEMBL27429987 | 0.66 | MAPT (0.48) | HTR2AL3MBTL1HPGDMAPTMAPK1 | |
| SCHEMBL11392121 | 0.62 | HTR2C (0.52) | HRH4HTR6L3MBTL1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |