Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 0.51 |
| ▸ | NUAK2 | Q9H093 | 2/20 | 0.51 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.51 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | BLK | P51451 | 1/20 | 0.42 |
| ▸ | BMX | P51813 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27429703 | 0.83 | NPC1 (0.48) | EGFRSRCNPC1RAB9AJAK3 | |
| SCHEMBL27429693 | 0.80 | BRAF (0.47) | EGFRSRCNPC1RAB9AJAK3 | |
| SCHEMBL27429690 | 0.74 | HRH4 (0.43) | — | |
| SCHEMBL1275994 | 0.72 | NPC1 (0.48) | EGFRNUAK2NUAK1SRCNPC1 | |
| SCHEMBL27429710 | 0.71 | HTR2C (0.64) | SRCSMN1; SMN2 | |
| SCHEMBL27429801 | 0.70 | JAK3 (0.47) | EGFRJAK3JAK2BLK | |
| SCHEMBL12806188 | 0.69 | NPC1 (0.51) | EGFRSRCNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29809871 | 0.69 | EGFR (0.57) | EGFRNUAK2NUAK1SRCJAK3 | |
| SCHEMBL31060495 | 0.68 | EGFR (1.00) | EGFRNUAK2NUAK1JAK3JAK2 | |
| SCHEMBL29714319 | 0.68 | NUAK2 (0.89) | EGFRNUAK2NUAK1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118607-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS | CHDI FOUNDATION, INC. (US) | 2024-06-06 | — | — | WO | disclosed |