SCHEMBL27429830

SCHEMBL27429830

CC1=Cc2c(cc(C(C)C)cc2C(C)C)[CH]1.Cl[Zr]Cl

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
FABP3 P05413 2/20 0.33
FABP4 P15090 2/20 0.33
FABP5 Q01469 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4837877 0.93 GABRA1 (0.38) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL28407137 0.91 GABRA1 (0.37) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27463389 0.90 GABRA1 (0.34) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27462015 0.87 GABRA1 (0.34) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27512801 0.85
SCHEMBL27497576 0.85
SCHEMBL27461594 0.80 GABRA1 (0.32) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27496567 0.78
SCHEMBL7175146 0.77 LMNA (0.32)
SCHEMBL27391250 0.75 GABRA1 (0.38) GABRA1GABRB2FABP3FABP4FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1946748-B Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECH HOLDINGS CV 2011-04-06 CN claimed
CN-1946748-A Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECH HOLDINGS CV (NL) 2007-04-11 CN claimed
CN-110167973-B High purity polypropylene for molding and polypropylene composition 道达尔研究技术弗吕公司 2022-06-17 CN disclosed
CN-101384624-B Catalyst composition for olefin polymerization NOVOLEN TECH HOLDINGS CV 2012-07-04 CN disclosed
CN-101316871-B Moulding composition comprising polyethylene for producing films and method for producing said moulding composition in the presence of a mixed catalyst BASELL POLYOLEFINE GMBH 2011-06-01 CN disclosed
CN-1946748-B Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECH HOLDINGS CV 2011-04-06 CN disclosed
CN-101511879-A Preparation of polymerization catalyst activators utilizing indole-modified silica supports EXXONMOBIL CHEM PATENTS INC (US) 2009-08-19 CN disclosed
CN-101384624-A Catalyst composition for olefin polymerization NOVOLEN TECH HOLDINGS CV (NL) 2009-03-11 CN disclosed
CN-101316871-A Moulding composition comprising polyethylene for producing films and method for producing said moulding composition in the presence of a mixed catalyst BASELL POLYOLEFINE GMBH (DE) 2008-12-03 CN disclosed
CN-1946748-A Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins NOVOLEN TECH HOLDINGS CV (NL) 2007-04-11 CN disclosed
CN-1160055-A Process for reducing by-product in product mixture HOECHST AG (DE) 1997-09-24 CN disclosed
CN-1107162-A Metallocen method for preparation of same and application of same as catalyst HOECHST AG (DE) 1995-08-23 CN disclosed