SCHEMBL4837877

SCHEMBL4837877

CC1=Cc2c(cc(C(C)C)cc2C(C)C)[CH]1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
FABP3 P05413 2/20 0.37
FABP4 P15090 2/20 0.37
FABP5 Q01469 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28407137 0.98 GABRA1 (0.37) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27429830 0.93 GABRA1 (0.34) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27462015 0.93 GABRA1 (0.34) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27463389 0.93 GABRA1 (0.34) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL7175146 0.82 LMNA (0.32)
SCHEMBL27391250 0.81 GABRA1 (0.38) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27737010 0.79 GABRA1 (0.37) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27365530 0.77 GABRA1 (0.35) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27394737 0.77 GABRA1 (0.35) GABRA1GABRB2FABP3FABP4FABP5
SCHEMBL27512801 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 141 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0779295-B1 Metallocenes BASELL POLYOLEFINE GMBH (DE) 2004-10-20 EP claimed
EP-0779306-B1 Process for preparation of cycloolefin copolymers TICONA GMBH (DE) 2003-12-03 EP claimed
EP-1134227-A2 Methylene-bridged biscyclopentadienyl compounds Basell Polyolefine GmbH (DE) 2001-09-19 EP claimed
US-6255508-B1 COORDINATION CATALYST; ALPHA-OLEFIN POLYMERIZATION CATALYST TARGOR GMBH (DE) 2001-07-03 US claimed
US-5945553-A Process for preparing a methylene-bridged biscyclopentadienyl compound TARGOR GMBH (DE) 1999-08-31 US claimed
US-5808122-A Organometallic compound HOECHST AKTIENGESELLSCHAFT (DE) 1998-09-15 US claimed
US-5726333-A POLYMERIZATION CATALYSTS HOECHST AG (DE) 1998-03-10 US claimed
WO-2022059765-A1 METHOD FOR PRODUCING ION-EXCHANGEABLE LAYERED SILICATE SALT PARTICLES, METHOD FOR PRODUCING OLEFIN POLYMERIZATION CATALYST COMPONENT, METHOD FOR PRODUCING OLEFIN POLYMERIZATION CATALYST, AND METHOD FOR PRODUCING OLEFIN POLYMER USING SAME 日本ポリプロ株式会社 2022-03-24 WO disclosed
WO-2020203274-A1 PRODUCTION METHOD FOR CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, PRODUCTION METHOD FOR CATALYST FOR OLEFIN POLYMERIZATION, AND PRODUCTION METHOD FOR OLEFIN POLYMER 日本ポリプロ株式会社 2020-10-08 WO disclosed
WO-2013158411-A1 METHODS OF SEPARATING COMPOUNDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-24 WO disclosed
US-20130276519-A1 Methods of Separating Compounds EXXONMOBIL CHEMICAL PATENTS INC. 2013-10-24 US disclosed
CN-100494269-C Solvent dispersion of composite resin and uses thereof MITSUI CHEMICALS INC (JP) 2009-06-03 CN disclosed
CN-100460422-C Catalytic components for polymerization of olefins, catalyst and process for the polymerization MARUZEN PETROCHEM CO LTD (JP) 2009-02-11 CN disclosed
EP-0704454-A2 Process for the preparation of a bridged metallocene HOECHST AKTIENGESELLSCHAFT (DE) 1996-04-03 EP disclosed
EP-0694557-A2 Organo metallic compounds HOECHST AKTIENGESELLSCHAFT (DE) 1996-01-31 EP disclosed
EP-0687682-A1 Transition metal compounds HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-20 EP disclosed
CN-1109061-A Metallocenic compound HOECHST AG (DE) 1995-09-27 CN disclosed
CN-1107854-A Metalocenes compound HOECHST AG (DE) 1995-09-06 CN disclosed
CN-1107162-A Metallocen method for preparation of same and application of same as catalyst HOECHST AG (DE) 1995-08-23 CN disclosed
EP-0654476-A1 Metallocenes, their preparation and use as catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1995-05-24 EP disclosed