SCHEMBL2742986

SCHEMBL2742986

CC(C)c1nccnc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28789380 0.80 APLNR (0.31)
SCHEMBL2732228 0.80 PIK3CG (0.31)
SCHEMBL1333708 0.77
SCHEMBL30202366 0.70 CYP2A6 (0.30)
SCHEMBL23602965 0.70 LMNA (0.34)
SCHEMBL1334181 0.70
SCHEMBL9963324 0.70 CYP2D6 (0.40)
SCHEMBL29952037 0.69
SCHEMBL2348392 0.69
SCHEMBL12304027 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024059096-A2 C5AR1 ANTAGONISTS AND USES THEREOF VANQUA BIO, INC. (US) 2024-03-21 WO disclosed
EP-3611165-A1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT Mitsui Chemicals Agro, Inc. (JP) 2020-02-19 EP disclosed
US-9434721-B2 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. (US) 2016-09-06 US disclosed
US-20140142112-A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN PURDUE PHARMA L.P. (US) 2014-05-22 US disclosed
US-8536177-B2 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. (US) 2013-09-17 US disclosed
US-20120004217-A1 THERAPEUTIC AGENTS USEFUL FOR TREATING PAIN PURDUE PHARMA L.P. (US) 2012-01-05 US disclosed
US-7683063-B2 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. (US) 2010-03-23 US disclosed
US-20070027159-A1 Therapeutic agents useful for treating pain PURDUE PHARMA L.P. 2007-02-01 US disclosed